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Deluged with mail after his discovery of the double helix, Francis Crick began sending a printed card in response to invitations:

crick demurral

He modeled it on a similar one made by Edmund Wilson:

wilson demurral

In 1976 freelance writer Betty Eppes managed to talk to J.D. Salinger for 20 minutes. “He said he didn’t believe in giving autographs. It was a meaningless gesture. He told me never to sign my name for anyone else. It was all right for actors and actresses to sign their names, because all they had to give were their faces and names. But it was different with writers. They had their work to give. Therefore, it was cheap to give autographs. He said, Don’t you ever do it! No self-respecting writer should ever do it.”

See Pen Fatigue.